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Anti-CPNE7 Purified

CPNE7 (copine VII) is a member of highly conserved copine family, which is composed of calcium-dependent membrane-binding proteins containing two N-terminal C domains and a C-terminal A domain (von Willenbrand domain) . There is an evidence that copines (at least copine III) may represent a novel unconventional kinase family. CPNE7 is expressed mainly in brain, but also in duodenum, jejunum, thymus and testes.

Product Specifications

Certification

RUO

Immunogen

Bacterially produced GST-fused C terminus of human CPNE7.

Target Antigen

CPNE7

Clone

CPNE7-01

Applications

WB

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Other References

*Cowland JB, Carter D, Bjerregaard MD, Johnsen AH, Borregaard N, Lollike K: Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils. J Leukoc Biol. 2003 Sep;74 (3) :379-88., URL: https://www.ncbi.nlm.nih.gov/pubmed/12949241?ordin, *Caudell EG, Caudell JJ, Tang CH, Yu TK, Frederick MJ, Grimm EA: Characterization of human copine III as a phosphoprotein with associated kinase activity. Biochemistry. 2000 Oct 24;39 (42) :13034-43., URL: https://www.ncbi.nlm.nih.gov/pubmed/11041869?ordin, *Savino M, d'Apolito M, Centra M, van Beerendonk HM, Cleton-Jansen AM, Whitmore SA, Crawford J, Callen DF, Zelante L, Savoia A: Characterization of copine VII, a new member of the copine family, and its exclusion as a candidate in sporadic breast cancers with loss of heterozygosity at 16q24.3. Genomics. 1999 Oct 15;61 (2) :219-26., URL: https://www.ncbi.nlm.nih.gov/pubmed/10534407?ordin

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody CPNE7-01 recognizes C terminus of human CPNE7, a calcium-binding cytoplasmic protein expressed mainly in brain.

Species

Human

CAS Number

9007-83-4

Isotype

Mouse IgG

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