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Anti-HLA-G Purified

Product Specifications

Clone

4H84

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Blaschitz A, Hutter H, Dohr G: HLA Class I protein expression in the human placenta. Early Pregnancy. 2001 Jan;5 (1) :67-9., URL: https://www.ncbi.nlm.nih.gov/pubmed/11753519?dopt=, *Urosevic M, Kurrer MO, Kamarashev J, Mueller B, Weder W, Burg G, Stahel RA, Dummer R, Trojan A: Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production. Am J Pathol. 2001 Sep;159 (3) :817-24., URL: https://www.ncbi.nlm.nih.gov/pubmed/11549573?dopt=, *Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64 (3) :315-26., URL: https://www.ncbi.nlm.nih.gov/pubmed/12590976?dopt=, *Polakova K, Krcova M, Kuba D, Russ G: Analysis of HLA-G expression in malignant hematopoetic cells from leukemia patients. Leuk Res. 2003 Jul;27 (7) :643-8., URL: https://www.ncbi.nlm.nih.gov/pubmed/12681364?dopt=, *Polakova K, Kuba D, Russ G: The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes. Hum Immunol. 2004 Feb;65 (2) :157-62., URL: https://www.ncbi.nlm.nih.gov/pubmed/14969770?dopt=, *Juch H, Blaschitz A, Daxbock C, Rueckert C, Kofler K, Dohr G: A novel sandwich ELISA for alpha1 domain based detection of soluble HLA-G heavy chains. J Immunol Methods. 2005 Dec 20;307 (1-2) :96-106., URL: https://www.ncbi.nlm.nih.gov/pubmed/16310801?dopt=, *Barrier BF, Kendall BS, Sharpe-Timms KL, Kost ER: Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma. Gynecol Oncol. 2006 Oct;103 (1) :25-30., URL: https://www.ncbi.nlm.nih.gov/pubmed/16530254?dopt=, *Paul P, Rouas-Freiss N, Khalil-Daher I, Moreau P, Riteau B, Le Gal FA, Avril MF, Dausset J, Guillet JG, Carosella ED: HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci U S A. 1998 Apr 14;95 (8) :4510-5., URL: https://www.ncbi.nlm.nih.gov/pubmed/9539768?dopt=A, *Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsí V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules. J Immunol. 2005 Oct 15;175 (8) :4866-74., URL: https://www.ncbi.nlm.nih.gov/pubmed/16210588?ordin, *Creput C, Le Friec G, Bahri R, Amiot L, Charpentier B, Carosella E, Rouas-Freiss N, Durrbach A: Detection of HLA-G in serum and graft biopsy associated with fewer acute rejections following combined liver-kidney transplantation: Possible implications for monitoring patients. Hum Immunol. 2003 Nov;64 (11) :1033-8., URL: https://pubmed.ncbi.nlm.nih.gov/14602232/, *Poláková K, Bennink JR, W Yewdell J, Bystrická M, Bandzuchová E, Russ G: Mild acid treatment induces cross-reactivity of 4H84 monoclonal antibody specific to nonclassical HLA-G antigen with classical HLA class I molecules. Hum Immunol. 2003 Feb;64 (2) :256-64., URL: https://pubmed.ncbi.nlm.nih.gov/12559628/, *Zhang X, Lin A, Han QY, Zhang JG, Chen QY, Ye YH, Zhou WJ, Xu HH, Gan J, Yan WH: Intratumor heterogeneity of HLA-G expression in cancer lesions. Front Immunol. 2020 Nov 19;11:565759., URL: https://pubmed.ncbi.nlm.nih.gov/33329527/, *Zhao L, Teklemariam T, Hantash BM: Reassessment of HLA-G isoform specificity of MEM-G/9 and 4H84 monoclonal antibodies. Tissue Antigens 2012 Sep;80 (3) :231-8., URL: https://pubmed.ncbi.nlm.nih.gov/22738368/

Other References

*Creput C, Durrbach A, Menier C, Guettier C, Samuel D, Dausset J, Charpentier B, Carosella ED, Rouas-Freiss N. Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation. J Hepatol. 2003 39 (4) :587-94., URL: https://pubmed.ncbi.nlm.nih.gov/12971970/, *Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, LeDanff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 64 (3) :315-26., URL: https://pubmed.ncbi.nlm.nih.gov/12590976/, *Lin A, Yan WH: Heterogeneity of HLA-G expression in cancers: Facing the challenges. Front Immunol. 2018 Sep 27;9:2164., URL: https://pubmed.ncbi.nlm.nih.gov/30319626/, *Hunt JS, Langat DK, McIntire RH, Morales PJ: The role of HLA-G in human pregnancy. Reprod Biol Endocrinol. 2006;4 Suppl 1 (Suppl 1) :S10., URL: https://pubmed.ncbi.nlm.nih.gov/17118165/, *Xu HH, Yan WH, Lin A: The role of HLA-G in human papillomavirus infections and cervical carcinogenesis. Front Immunol. 2020 Jun 25;11:1349., URL: https://pubmed.ncbi.nlm.nih.gov/32670296/, *Castelli EC, de Almeida BS, Muniz YC, Silva NS, Passos MR, Souza AS, Page AE, Dyble M, Smith D, Aguileta G, Bertranpetit J, Migliano AB, Duarte YA, Scliar MO, Wang J, Passos-Bueno MR, Naslavsky MS, Zatz M, Mendes CT, Donadi EA: HLA-G genetic diversity and evolutive aspects in worldwide populations. Sci Rep. 2021 Nov 29;11 (1) :23070., URL: https://pubmed.ncbi.nlm.nih.gov/34845256/, *Curigliano G, Criscitiello C, Gelao L, Goldhirsch A: Molecular pathways: Human leukocyte antigen G (HLA-G) . Clin Cancer Res. 2013 Oct 15;19 (20) :5564-71., URL: https://pubmed.ncbi.nlm.nih.gov/23897901/

CAS Number

9007-83-4

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