Anti-NTAL Purified
NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Product Specifications
Certification
RUO
Negative Species
Human
Reactivity
Mouse
Immunogen
Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.
Target Antigen
NTAL
Clone
PAb (486)
Applications
WB
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Western blotting: Recommended dilution: 1 μg/ml; positive control: murine spleen; non-reducing conditions.
Isotype
Rabbit polyclonal
Frequently Asked Questions
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