Anti-SYK Purified

*Osicka R, Osickova A, Hasan S, Bumba L, Cerny J, Sebo P: Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3. Elife. 2015 Dec 9;4:e10766., URL: https://www.ncbi.nlm.nih.gov/pubmed/26650353 , *Heneberg P, Lebduška P, Draberova L, Korb J, Draber P: Topography of plasma membrane microdomains and its consequences for mast cell signaling. Eur J Immunol. 2006 Oct;36 (10) :2795-806. , URL: https://www.ncbi.nlm.nih.gov/pubmed/17013982?dopt=, *Halova I, Draberova L, Draber P: A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor. Int Immunol. 2002 Feb;14 (2) :213-23., URL: https://www.ncbi.nlm.nih.gov/pubmed/11809740?dopt=, *Arudchandran R, Brown MJ, Peirce MJ, Song JS, Zhang J, Siraganian RP, Blank U, Rivera J: The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH (2) -terminal kinase 1. J Exp Med. 2000 Jan 3;191 (1) :47-60., URL: https://www.ncbi.nlm.nih.gov/pubmed/10620604?dopt=

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The antibody SYK-01 reacts with protein tyrosine kinase p72Syk (Syk; an intracellular antigen), which is required for the transduction of signals through the B cell antigen receptor (BCR) and the high affinity IgE receptor (FcepsilonRI) .