Anti-Benzo[a]pyrene Purified

Product Specifications

Certification

RUO

Immunogen

Benzo[a]pyrenyl-1-butyric acid conjugated to BSA.

Target Antigen

Benzo[a]pyrene

Clone

BAP-13

Applications

ICC, ELISA

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Suchanek M, Scharnweber T, Fisher M, Knopp D, Niessner R: Monoclonal antibodies specific to polynuclear aromatic hydrocarbons. Folia Biol (Praha) . 2001;47 (3) :106-7., URL: , *Scharnweber T, Fisher M, Suchanek M, Knopp D, Niessner R: Monoclonal antibody to polycyclic aromatic hydrocarbons based on a new benzo[a]pyrene immunogen. Fresenius J Anal Chem. 2001 Nov;371 (5) :578-85., URL: https://www.ncbi.nlm.nih.gov/pubmed/11767882?dopt=, *De Buck SS, Bouche FB, Brandenburger A, Muller CP: Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis? Carcinogenesis. 2005 Apr;26 (4) :835-44., URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15637092&query_hl=1&itool=pubmed_docsum

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The antibody BAP-13 is specific for Polynuclear Aromatic Hydrocarbon and inhibits DNA adduct formation (this ability was investigated in rat liver microsomes spiked with calf thymus DNA and 7,8-diol-B[a]P) .

Applications Notes

Immunocytochemistry: The antibody BAP-13 is suitable for immunocytochemical analysis of DNA and protein adducts of benzo[a]pyrene in tissues of various species.