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Anti-PSA Purified

Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.

Product Specifications

Certification

RUO

Immunogen

30 kDa protein fraction prepared from human seminal plasma

Target Antigen

PSA

Clone

A67-B/E3

Applications

WB, IHC-P, ELISA

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody A67-B/E3 reacts with prostate-specific antigen (PSA), a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid. This antibody recognizes both free and complexed PSA.

Applications Notes

Western blotting: Positive material: seminal plasma, reducing conditions, recommended antibody dilution: 2-5 μg/ml.

Species

Human

CAS Number

9007-83-4

Isotype

Mouse IgG1

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