What is the catalog number for Anti-NG2 Purified?

The catalog number for Anti-NG2 Purified is 11-199-C100.

What sizes are available for Anti-NG2 Purified?

Anti-NG2 Purified is available in the following size(s): 0.1 mg.

Is Anti-NG2 Purified in stock?

Anti-NG2 Purified is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-NG2 Purified?

Anti-NG2 Purified is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-NG2 Purified?

Estimated delivery time for Anti-NG2 Purified is approximately 10 business day(s), depending on your location.

Anti-NG2 Purified

NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

Human bone marrow stromal cells infected with SV-40

Target Antigen

NG2

Clone

7.1

Applications

FC (QC tested), IP, WB, ICC

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Cattaruzza S, Nicolosi PA, Braghetta P, Pazzaglia L, Benassi MS, Picci P, Lacrima K, Zanocco D, Rizzo E, Stallcup WB, Colombatti A, Perris R: NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion. J Mol Cell Biol. 2013 Jun;5 (3) :176-93., URL: https://pubmed.ncbi.nlm.nih.gov/23559515/, *Girolamo F, Dallatomasina A, Rizzi M, Errede M, Wälchli T, Mucignat MT, Frei K, Roncali L, Perris R, Virgintino D: Diversified expression of NG2/CSPG4 isoforms in glioblastoma and human foetal brain identifies pericyte subsets. PLoS One. 2013 Dec 26;8 (12) :e84883., URL: http://www.ncbi.nlm.nih.gov/pubmed/24386429 Emeren, *Petrovici K, Graf M, Hecht K, Reif S, Pfister K, Schmetzer H: Use of NG2 (7.1) in AML as a tumor marker and its association with a poor prognosis. Cancer Genomics Proteomics. 2010 Jul-Aug;7 (4) :173-80., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=petrovici+k+graf+m+hecht+k

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.