Anti-Hu CD57 Purified
CD57, also known as HNK1 or Leu7, is a sulphated trisaccharide (3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc) attached to several glycoproteins, including CD56, myelin glycoprotein PO, and neural cell adhesion molecule L1, as well as on glycolipids and chondroitin sulphate proteoglycans in the nervous system. It serves as a NK cell marker and it is expressed on well differentiated prostate cancers and uveal and cutaneous melanoma. CD57+ T cells are implicated as suppressors of T-cell responses.
Product Specifications
Certification
RUO
Immunogen
A pool of neuroblastoma cell lines
Target Antigen
CD57
Clone
TB01
Applications
FC (QC tested), WB, IHC-P, IHC-F, ICC
Concentration
1 mg/mL
Format
Purified
Buffer
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
The mouse monoclonal antibody TB01 recognizes CD57, a carbohydrate extracellular antigen present mainly on NK cells, NK T cells, and in neural tissue.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgM
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