Anti-Hu CD134 Purified
CD134 (TNFRSF4, also known as OX40) is a type I transmembrane glycoprotein of TNF/NGF receptor family expressed on activated T cells, fibroblasts, and hematopoietic precursors. Binding to its ligand (OX40L, TNFSF4) on antigen presenting cells gives to the T cell costimulatory signal, and this interaction results also in B cell proliferation and influences T cell memory pool. CD134 is upregulated at sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.
Product Specifications
Certification
RUO
Reactivity
Non-human primates, Human
Immunogen
HTLV 1-transformed HUT-102 cells
Target Antigen
CD134
Clone
Ber-ACT35
Applications
FC (QC tested), IP, WB, IHC-P, IHC-F, ELISA
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 3-6 μg/ml. Immunohistochemistry: Recommended dilution: 5-10 μg/ml.
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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