Anti-Hu CD102 Purified
CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human CD102 cDNA transfected COS cells
Target Antigen
CD102
Clone
CBR-IC2/2
Applications
FC (QC tested), IP, IHC-F
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 2-4 μg/ml.
Isotype
Mouse IgG2a
Frequently Asked Questions
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