Anti-Hu CD89 Purified

*Barratt J, Greer MR, Pawluczyk IZ, Allen AC, Bailey EM, Buck KS, Feehally J: Identification of a novel Fcalpha receptor expressed by human mesangial cells. Kidney Int. 2000 May;57 (5) :1936-48., URL: https://www.ncbi.nlm.nih.gov/pubmed/10792612, *Wu J, Ji C, Xie F, Langefeld CD, Qian K, Gibson AW, Edberg JC, Kimberly RP: FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA. J Immunol. 2007 Mar 15;178 (6) :3973-82., URL: https://pubmed.ncbi.nlm.nih.gov/17339498/, *Rogers KA, Scinicariello F, Attanasio R: Identification and characterization of macaque CD89 (immunoglobulin A Fc receptor) . Immunology. 2004 Oct;113 (2) :178-86. , URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17825, *van Dijk TB, Bracke M, Caldenhoven E, Raaijmakers JA, Lammers JW, Koenderman L, de Groot RP: Cloning and characterization of Fc alpha Rb, a novel Fc alpha receptor (CD89) isoform expressed in eosinophils and neutrophils. Blood. 1996 Dec 1;88 (11) :4229-38., URL: http://www.ncbi.nlm.nih.gov/pubmed/8943858 , *van Egmond M, van Spriel AB, Vermeulen H, Huls G, van Garderen E, van de Winkel JG: Enhancement of polymorphonuclear cell-mediated tumor cell killing on simultaneous engagement of fcgammaRI (CD64) and fcalphaRI (CD89) . Cancer Res. 2001 May 15;61 (10) :4055-60., URL: https://pubmed.ncbi.nlm.nih.gov/11358825/, *Honorio-França AC, Launay P, Carneiro-Sampaio MM, Monteiro RC: Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA. J Leukoc Biol. 2001 Feb;69 (2) :289-96., URL: https://www.ncbi.nlm.nih.gov/pubmed/11272280, *Schenk M, Bouchon A, Seibold F, Mueller C: TREM-1--expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases. J Clin Invest. 2007 Oct;117 (10) :3097-106., URL: https://www.ncbi.nlm.nih.gov/pubmed/17853946

The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages.