Anti-Ms MHC Class II Purified Azide Free

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The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.

Functional application: Blocking of T cell proliferative responses. Flow cytometry: Recommended dilution: 2 μg/ml. Immunohistochemistry: Recommended dilution: 5-10 μg/ml.