Anti-Hu CD59 Purified Azide Free
CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC) . It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.
Product Specifications
Certification
RUO
Immunogen
Human peripheral blood lymphocytes
Target Antigen
CD59
Clone
MEM-129
Applications
FC (QC tested), FUNC
Concentration
1 mg/mL
Format
Purified Azide Free
Buffer
Tris buffered saline (TBS), pH 8.0
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Species
Pig, Human
CAS Number
9007-83-4
Isotype
Mouse IgM
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