POVPC

POVPC is an oxidized phospholipid can be found in in oxidatively modified low density lipoprotein (oxLDL) . POVPC inhibits VSMC growth in high serum condition. POVPC induces apoptosis in low serum condition[1].

Product Specifications

CAS Number

[121324-31-0]

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/povpc.html

Concentration

8.42 mM * 200 μL in Ethanol

Purity

99.9

Solubility

10 mM in DMSO

Smiles

C[N+](C)(C)CCOP(OC[C@H](OC(CCCC=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O

Molecular Formula

C29H56NO9P

Molecular Weight

593.73

Precautions

H225, H319

References & Citations

[1]Fruhwirth GO, et al. The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 2006 Sep;1761 (9) :1060-9.