POVPC
POVPC is an oxidized phospholipid can be found in in oxidatively modified low density lipoprotein (oxLDL) . POVPC inhibits VSMC growth in high serum condition. POVPC induces apoptosis in low serum condition[1].
Product Specifications
CAS Number
[121324-31-0]
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/povpc.html
Concentration
8.42 mM * 200 μL in Ethanol
Purity
99.9
Solubility
10 mM in DMSO
Smiles
C[N+](C)(C)CCOP(OC[C@H](OC(CCCC=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O
Molecular Formula
C29H56NO9P
Molecular Weight
593.73
Precautions
H225, H319
References & Citations
[1]Fruhwirth GO, et al. The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 2006 Sep;1761 (9) :1060-9.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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