Fendosal

Fendosal (HP 129) is an orally active, potent non-steroidal anti-inflammatory agent. Fendosal (HP 129) is also an inhibitor of Plasminogen activator inhibitor-1 (PAI-1) [1].

Product Specifications

CAS Number

[53597-27-6]

Product Name Alternative

HP 129; P 71-0129

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PAI-1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fendosal.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(N2C(C3=CC=CC=C3)=CC4=C2CCC5=C4C=CC=C5)=CC=C1O)O

Molecular Formula

C25H19NO3

Molecular Weight

381.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]H B Lassman, et al. Fendosal (HP 129) : a potent anti-inflammatory and analgesic compound. Agents Actions. 1978 Apr;8 (3) :209-17.|[2]Ann Gils, et al. Plasminogen activator inhibitor-1. Curr Med Chem. 2004 Sep;11 (17) :2323-34.