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Anti-inflammatory agent 86

Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC50 of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-86.html

Smiles

O=C(N1CCN(CCOC2=CC(OC(C3=CC=CC=C3)=CC4=O)=C4C(O)=C2)CC1)CCCCC5CCSS5

Molecular Formula

C29H34N2O5S2

Molecular Weight

554.72

References & Citations

[1]Pengyu Zhao, et al. Synthesis and biological evaluation of chrysin derivatives containing α-lipoic acid for the treatment of inflammatory bowel disease. Front Chem. 2024 May 27:12:1406051.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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