Anti-inflammatory agent 86
Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC50 of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-86.html
Smiles
O=C(N1CCN(CCOC2=CC(OC(C3=CC=CC=C3)=CC4=O)=C4C(O)=C2)CC1)CCCCC5CCSS5
Molecular Formula
C29H34N2O5S2
Molecular Weight
554.72
References & Citations
[1]Pengyu Zhao, et al. Synthesis and biological evaluation of chrysin derivatives containing α-lipoic acid for the treatment of inflammatory bowel disease. Front Chem. 2024 May 27:12:1406051.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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