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Aristolochic acid B (Standard)

Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B. This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510)[2][3].

Product Specifications

CAS Number

475-80-9

Product Name Alternative

Aristolochic acid II (Standard)

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aristolochic-acid-b-standard.html

Smiles

O=C(C1=C2C([N+]([O-])=O)=CC3=CC=CC=C3C2=C(OCO4)C4=C1)O

Molecular Formula

C16H9NO6

Molecular Weight

311.25

References & Citations

[1]Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743 (1-2) :52-8.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Frequently Asked Questions

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