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TRH-βNA

Product Specifications

UNSPSC Description

TRH-βNA is a substrate for determining the membrane TRH-deamidating enzyme (TRH-DE) activity and membrane pyroglutamyl aminopeptidase II (PPII) activity[1][2].

Target Antigen

Biochemical Assay Reagents

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/trh-βna.html

Solubility

H2O

Smiles

O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(NC4=CC5=C(C=CC=C5)C=C4)=O)=O

Molecular Weight

488.54

References & Citations

[1]Müller-Fielitz H, et al. Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis. Nat Commun. 2017 Sep 7;8(1):484.|[2]Alvarez-Salas E, et al. Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. Endocrinology. 2012 Aug;153(8):4067-76.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P4584/TRH-βNA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P4584/

Clinical Information

No Development Reported

CAS Number

73644-58-3

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