LK-732
LK-732 is a thrombin inhibitor with anti-thrombotic activity.LK-732 has a dose-dependent inhibition of hypercoagulability in the model, with an IC50 of 1.3 mg/kg. LK-732 can be used in cardiovascular and cerebrovascular research[1].
Product Specifications
CAS Number
673485-33-1
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lk-732.html
Smiles
O=C(N1CCCCCC1)N(CC2=CC(C(N)=N)=CC=C2)NS(=O)(C3=CC4=C(C=CC=C4)C=C3)=O
Molecular Formula
C25H29N5O3S
Molecular Weight
479.59
References & Citations
[1]Peternel L, et al. Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models. Thromb Haemost. 2005 Mar;93 (3) :437-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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