Allocholic acid

Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite[1][2][3].

Product Specifications

CAS Number

[2464-18-8]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/allocholic-acid.html

Purity

99.76

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C

Molecular Formula

C24H40O5

Molecular Weight

408.57

References & Citations

[1]ThomasBriggs, et al. Allocholic acid, the major component in bile from the river carpsucker, Carpiodes carpio (Rafinesque) (Catostomidae) . Comp Biochem Physiol B. 1972 Jul 15;42 (3) :493-6.|[2]Li W, et al. The olfactory system of migratory adult sea lamprey (Petromyzon marinus) is specifically and acutely sensitive to unique bile acids released by conspecific larvae. J Gen Physiol. 1995 May;105 (5) :569-87.|[3]Mendoza ME, et al. Physiological characteristics of allo-cholic acid. J Lipid Res. 2003 Jan;44 (1) :84-92.|[4]Ridlon JM, et al. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 2010 Apr;16 (2) :137-46.|[5]Elliott WH, Hyde PM. Metabolic pathways of bile acid synthesis. Am J Med. 1971 Nov;51 (5) :568-79.