cyt-PTPε Inhibitor-1
Product Specifications
UNSPSC Description
cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1].
Target Antigen
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyt-ptp-epsilon-inhibitor-1.html
Purity
98.05
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C)C=C1)NC2=NN=C(COC3=CC=C(C)C=C3C)S2
Molecular Weight
368.462
References & Citations
[1]Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112800/cyt-PTPε-Inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112800/cyt-PTPε-Inhibitor-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
428478-94-8
Available Sizes
Curated Selection
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