Cyt-PTPε Inhibitor-1

Cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1].

Product Specifications

CAS Number

[428478-94-8]

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cyt-ptp-epsilon-inhibitor-1.html

Purity

98.05

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(C)C=C1)NC2=NN=C(COC3=CC=C(C)C=C3C)S2

Molecular Formula

C19H20N4O2S

Molecular Weight

368.46

References & Citations

[1]Ku B, et al. Identification of N- (5- (phenoxymethyl) -1,3,4-thiadiazol-2-yl) acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26 (18) :5204-5211.