Cyt-PTPε Inhibitor-1
Cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1].
Product Specifications
CAS Number
[428478-94-8]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyt-ptp-epsilon-inhibitor-1.html
Purity
98.05
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C)C=C1)NC2=NN=C(COC3=CC=C(C)C=C3C)S2
Molecular Formula
C19H20N4O2S
Molecular Weight
368.46
References & Citations
[1]Ku B, et al. Identification of N- (5- (phenoxymethyl) -1,3,4-thiadiazol-2-yl) acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26 (18) :5204-5211.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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