Salbutamol-d3

Salbutamol-d3 (Albuterol-d3) is the deuterium labeled Salbutamol (HY-B1037) . Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2].

Product Specifications

CAS Number

[1219798-60-3]

Product Name Alternative

Albuterol-d3; AH-3365-d3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; ERK; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; Neuronal Signaling; Others; Stem Cell/Wnt

Field of Research

Cancer; Inflammation/Immunology

Purity

98.68

Solubility

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

Smiles

OC([2H])([2H])C1=C(O)C=CC(C(CNC(C)(C)C)([2H])O)=C1

Molecular Formula

C13H18D3NO3

Molecular Weight

242.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13 (2) :401-412.|[2]Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47 (6) :436-445.