[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P

<strong>[D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance P</strong> <strong>Catalog number:</strong> MDP0556 <strong>CAS Number: </strong>150769-72-5 <strong>Sequence: </strong>D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 1497.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Woll PJ, Rozengurt E. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro Proc Natl Acad Sci U S A. 1988 Mar;85(6):1859-63. 2: Watson SP. Pharmacological characterization of a substance P antagonist, [D-Arg1,D-Pro2,D-Trp7,9,Leu11]-substance P Br J Pharmacol. 1983 Sep;80(1):205-9. 3: Surprenant A, North RA, Katayama Y. Observations on the actions of substance P and [D-Arg1,D-Pro2,D-Trp7,9,Leu11)substance P on single neurons of the guinea pig submucous plexus Neuroscience. 1987 Jan;20(1):189-99. 4: Bobyock E, Barbieri EJ, Chernick WS. Effects of substance P and substance P antagonists on rat salivary secretion J Dent Res. 1986 Dec;65(12):1427-31. 5: Jensen RT, Jones SW, Lu YA, Xu JC, Folkers K, Gardner JD. Interaction of substance P antagonists with substance P receptors on dispersed pancreatic acini Biochim Biophys Acta. 1984 Jun 19;804(2):181-91. 6: Galligan JJ, Jiang MM, Shen KZ, Surprenant A. Substance P mediates neurogenic vasodilatation in extrinsically denervated guinea-pig submucosal arterioles J Physiol. 1990 Jan;420:267-80. 7: Costa M, Furness JB, Pullin CO, Bornstein J. Substance P enteric neurons mediate non-cholinergic transmission to the circular muscle of the guinea-pig intestine Naunyn Schmiedebergs Arch Pharmacol. 1985 Feb;328(4):446-53. 8: Jones SW. Muscarinic and peptidergic excitation of bull-frog sympathetic neurones J Physiol. 1985 Sep;366:63-87. 9: Brock JW, Joshua IG. Neural release of substance P causes dilation of arterioles in rat striated muscle Regul Pept. 1993 Jan 22;43(1-2):65-71. <a href="https://pubmed.ncbi.nlm.nih.gov/2481406">10: Kawatani M, Whitney T, Booth AM, de Groat WC. Excitatory effect of substance P in parasympathetic ganglia of cat urinary bladder Am J Physiol. 1989 Dec;257(6 Pt 2):R1450-6. </a> <br><strong>Products Related to [D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance P can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>