Plectasin

<strong>Plectasin</strong> <strong>Catalog number:</strong> MDP0793 <strong>CAS Number: </strong>179667-62-0 <strong>Sequence: </strong>Gly-Phe-Gly-Cys-Asn-Gly-Pro-Trp-Asp-Glu-Asp-Asp-Met-Gln-Cys-His-Asn-His-Cys-Lys-Ser-Ile-Lys-Gly-Tyr-Lys-Gly-Gly-Tyr-Cys-Ala-Lys-Gly-Gly-Phe-Val-Cys-Lys-Cys-Tyr (Disulfide bonds between Cys4-Cys30, Cys15-Cys37, and Cys19-Cys39) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 4401.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Liang X, Jiang H, Si X, Xin Q, Meng D, Chen P, Mao X. Boosting expression level of plectasin in recombinant Pichia pastoris via 2A self-processing peptide assembly Appl Microbiol Biotechnol. 2022 May;106(9-10):3669-3678. 2: Ko SKK, Paraso MGV, Pajas AMGA, Dela Cruz JF. Immunomodulatory responses in plectasin-supplemented broilers under tropical environmental conditions Trop Anim Health Prod. 2021 Apr 9;53(2):253. 3: Xiang F, Xie Z, Feng J, Yang W, Cao Z, Li W, Chen Z, Wu Y. Plectasin, first animal toxin-like fungal defensin blocking potassium channels through recognizing channel pore region Toxins (Basel). 2015 Jan 5;7(1):34-42. 4: Zhang L, Li X, Wei D, Wang J, Shan A, Li Z. Expression of plectasin in Bacillus subtilis using SUMO technology by a maltose-inducible vector J Ind Microbiol Biotechnol. 2015 Oct;42(10):1369-76. 5: Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH. Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II Science. 2010 May 28;328(5982):1168-72. 6: Hara S, Mukae H, Sakamoto N, Ishimoto H, Amenomori M, Fujita H, Ishimatsu Y, Yanagihara K, Kohno S. Plectasin has antibacterial activity and no affect on cell viability or IL-8 production Biochem Biophys Res Commun. 2008 Oct 3;374(4):709-13. 7: Pohl C, Effantin G, Kandiah E, Meier S, Zeng G, Streicher W, Segura DR, Mygind PH, Sandvang D, Nielsen LA, Peters GHJ, Schoehn G, Mueller-Dieckmann C, Noergaard A, Harris P. pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils Nat Commun. 2022 Jun 7;13(1):3162. 8: Zhang X, Zhao Q, Wen L, Wu C, Yao Z, Yan Z, Li R, Chen L, Chen F, Xie Z, Chen F, Xie Q. The Effect of the Antimicrobial Peptide Plectasin on the Growth Performance, Intestinal Health, and Immune Function of Yellow-Feathered Chickens Front Vet Sci. 2021 Jun 23;8:688611. 9: Chen X, Hu YH, Chen WD, Li WD, Huang ZC, Li Y, Luo YW, Huang YX, Chen YT, Wang K, Li L. Comparison of inducible versus constitutive expression of plectasin on yields and antimicrobial activities in Pichia pastoris Protein Expr Purif. 2016 Feb;118:70-6. <a href="https://pubmed.ncbi.nlm.nih.gov/16222292">10: Mygind PH, Fischer RL, Schnorr KM, Hansen MT, Sönksen CP, Ludvigsen S, Raventós D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-Jørgensen SG, Sørensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen HH. Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus Nature. 2005 Oct 13;437(7061):975-80. </a> <br><strong>Products Related to Plectasin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>