Peonidin 3-O-glucoside (chloride)

Peonidin 3-O-glucoside chloride is an agonist of the free fatty acid receptor FFAR1 and Glucokinase. Peonidin 3-O-glucoside chloride enhances insulin secretion of pancreatic beta cells and increases glucose uptake by liver cells. Peonidin 3-O-glucoside chloride activates FFAR1, promotes the phosphorylation of related proteins in the insulin secretion pathway, and increases the expression of FFAR1. In liver cells, Peonidin 3-O-glucoside chloride activates GK and regulates proteins associated with carbohydrate metabolism. Peonidin 3-O-glucoside chloride can be used in diabetes research[1][2].

Product Specifications

CAS Number

[6906-39-4]

UNSPSC

12352005

Target

Insulin Receptor

Type

Natural Products

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/peonidin-3-o-glucoside-chloride.html

Purity

98.02

Solubility

DMSO : 31.25 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC(O)=CC2=C1C=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(C4=CC=C(O)C(OC)=C4)=[O+]2.[Cl-]

Molecular Formula

C22H23ClO11

Molecular Weight

498.86

References & Citations

[1]Diego A Luna-Vital, et al. Anthocyanins from purple corn activate free fatty acid-receptor 1 and glucokinase enhancing in vitro insulin secretion and hepatic glucose uptake. PLoS One. 2018 Jul 11;13 (7) :e0200449.|[2]Wu G, et al. Optimized Synthesis and Antioxidant Activity of Anthocyanins Delphinidin-3-O-glucoside and Petunidin-3-O-glucoside. J Agric Food Chem. 2024 Jul 3;72 (26) :15005-15012.