VCP171
VCP171 is a potent adenosine A1 receptor (A1R) positive allosteric modulator (PAM) . VCP171 is effective at decreasing excitatory synaptic currents in Lamina II of neuropathic pain model. VCP171 can be used for researching neuropathic pain[1].
Product Specifications
CAS Number
1018830-99-3
Product Name Alternative
BYK61359,AZD-0865 (mesylate)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vcp171.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(N)SC=C1C2=CC(C(F)(F)F)=CC=C2)C3=CC=CC=C3
Molecular Formula
C18H12F3NOS
Molecular Weight
347.35
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Imlach WL, et al. A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model. Mol Pharmacol. 2015 Sep;88 (3) :460-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A1 receptor (A1R)
Available Sizes
Frequently Asked Questions
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