MOCAc-PLGL (Dpa) AR

MOCAc-PLGL (Dpa) AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL (Dpa) AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues[1][2].

Product Specifications

CAS Number

[140430-53-1]

Product Name Alternative

Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mocac-plgl-dpa-ar.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N=C(N)NCCC[C@@H](C(N)=O)NC([C@H](C)NC([C@H](CNC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC(C)C)NC([C@H]2N(C(CC(C3=CC=C(OC)C=C3O4)=CC4=O)=O)CCC2)=O)=O)=O)=O)=O)=O

Molecular Formula

C49H68N14O15

Molecular Weight

1093.15

References & Citations

[1]Oneda H, et al. Substrate-dependent activation of thermolysin by salt. Biosci Biotechnol Biochem. 2004 Aug;68 (8) :1811-3.|[2]Oneda H, et al. Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (matrilysin) . J Biochem. 2003 May;133 (5) :571-6.