Human BCL2L11 Protein

<strong>Human BCL2L11 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011635_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.5 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> BIM-beta6 protein, BCLL11-2, BimL protein, BIM-alpha6 protein, BimEL protein, BAM protein, BCLL11 2, BCLL11 2 protein, BCL2-like 11 protein, BIM-beta7 protein, BOD protein, BCL2L11, BCLL11-2 protein, BIM protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Julien O, Wells JA. Caspases and their substrates Cell Death Differ. 2017 Aug;24(8):1380-1389._x000D_ 2: Tanaka K, Yu HA, Yang S, Han S, Selcuklu SD, Kim K, Ramani S, Ganesan YT, Moyer A, Sinha S, Xie Y, Ishizawa K, Osmanbeyoglu HU, Lyu Y, Roper N, Guha U, Rudin CM, Kris MG, Hsieh JJ, Cheng EH. Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis Cancer Cell. 2021 Sep 13;39(9):1245-1261.e6._x000D_ 3: Edlich F. BCL-2 proteins and apoptosis: Recent insights and unknowns Biochem Biophys Res Commun. 2018 May 27;500(1):26-34._x000D_ 4: Fevereiro J, Fraga AG, Capela C, Sopoh GE, Dossou A, Ayelo GA, Peixoto MJ, Cunha C, Carvalho A, Rodrigues F, Pedrosa J. Genetic variants in human BCL2L11 (BIM) are associated with ulcerative forms of Buruli ulcer Emerg Microbes Infect. 2021 Dec;10(1):223-225._x000D_ 5: Wang L, Wang S, Shi Y, Li R, Günther S, Ong YT, Potente M, Yuan Z, Liu E, Offermanns S. YAP and TAZ protect against white adipocyte cell death during obesity Nat Commun. 2020 Oct 28;11(1):5455._x000D_ 6: Zhu R, Li L, Nguyen B, Seo J, Wu M, Seale T, Levis M, Duffield A, Hu Y, Small D. FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation Signal Transduct Target Ther. 2021 May 24;6(1):186._x000D_ 7: Sur S, Steele R, Shi X, Ray RB. miRNA-29b Inhibits Prostate Tumor Growth and Induces Apoptosis by Increasing Bim Expression Cells. 2019 Nov 18;8(11):1455._x000D_ 8: Gaviraghi M, Caricasole A, Costanzo C, Diamanti D, Dandrea M, Donadelli M, Scarpa A, Palmieri M. Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene BMC Mol Biol. 2008 Jun 12;9:56._x000D_ 9: Zhang YY, Xiong GY, Xie XX. MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells Biosci Rep. 2021 Jun 25;41(6):BSR20201397._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32605511">10: Huang J, Huang Y, Feng Z, Guo W, Wang X, Liao Z. MiR-1247-3p protects rat cardiomyocytes against hypoxia/reoxygenation-induced injury via targeting BCL2L11 and caspase-2 J Recept Signal Transduct Res. 2021 Feb;41(1):6-14. </a>_x000D_ _x000D_ <strong>Products Related to Human BCL2L11 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>