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(-) -Zuonin A

(-) -Zuonin A (D-Epigalbacin), a naturally occurring lignin, is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively[1].

Product Specifications

CAS Number

84709-25-1

Product Name Alternative

D-Epigalbacin

UNSPSC

12352005

Target

JNK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/minus-zuonin-a.html

Purity

99.99

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@H]1[C@@H](C)[C@@H](C2=CC=C(OCO3)C3=C2)O[C@@H]1C4=CC=C(OCO5)C5=C4

Molecular Formula

C20H20O5

Molecular Weight

340.37

References & Citations

[1]Tamer S. Kaoud, et al. Manipulating JNK Signaling with (−) -zuonin A. ACS Chem Biol. 2012 Nov 16; 7 (11) : 1873–1883.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

JNK1; JNK2; JNK3

Frequently Asked Questions

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