(RS) -APICA
(RS) -APICA is a selective group II metabotropic glutamate receptor (mGluR II) antagonist. (RS) -APICA shows potential neuroprotective effect[1].
Product Specifications
CAS Number
[170847-18-4]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/apica.html
Purity
99.99
Solubility
0.1 M NaOH : 6.25 mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 60°C)
Smiles
O=C(C1(N)CCC2=C1C=CC(P(O)(O)=O)=C2)O
Molecular Formula
C10H12NO5P
Molecular Weight
257.18
References & Citations
[1]Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71 (4) :192-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2
Available Sizes
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