Glycinexylidide
Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].
Product Specifications
CAS Number
[18865-38-8]
Product Name Alternative
GX
UNSPSC
12352200
Hazard Statement
H315, H319
Target
Drug Metabolite; ERK; MEK; NF-κB; Sodium Channel
Type
Biochemical Assay Reagents
Related Pathways
MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glycinexylidide.html
Concentration
10mM
Purity
95.06
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=C(C)C=CC=C1C)CN
Molecular Formula
C10H14N2O
Molecular Weight
178.23
Precautions
H315, H319
References & Citations
[1]Strong JM, et al. Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther. 1975 Feb;17 (2) :184-94.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 3
Available Sizes
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