Human AAGAB Protein

<strong>Human AAGAB Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011523_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 36.7 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> AAGAB protein (His tag), AAGAB, Alpha- and gamma-adaptin-binding p34 protein, P34 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Gulbranson DR, Crisman L, Lee M, Ouyang Y, Menasche BL, Demmitt BA, Wan C, Nomura T, Ye Y, Yu H, Shen J. AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis Dev Cell. 2019 Aug 19;50(4):436-446.e5._x000D_ 2: Charfeddine C, Ktaifi C, Laroussi N, Hammami H, Jmel H, Landoulsi Z, Badri T, Benmously R, Bchetnia M, Boubaker MS, Fenniche S, Abdelhak S, Mokni M. Clinical and molecular investigation of Buschke-Fischer-Brauer in consanguineous Tunisian families J Eur Acad Dermatol Venereol. 2016 Dec;30(12):2122-2130._x000D_ 3: Li M, Yang L, Shi H, Guo B, Dai X, Yao Z, Zhang G. Loss-of-function mutation in AAGAB in Chinese families with punctuate palmoplantar keratoderma Br J Dermatol. 2013 Jul;169(1):168-71._x000D_ 4: Dai C, Wu B, Chen Y, Li X, Bai Y, Du Y, Pang Y, Wang YT, Dong Z. Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage Cell Death Differ. 2021 Aug;28(8):2367-2384._x000D_ 5: Dereure O. [Keratinisation disorders: new data] Ann Dermatol Venereol. 2013 Feb;140(2):150-1._x000D_ 6: Pohler E, Mamai O, Hirst J, Zamiri M, Horn H, Nomura T, Irvine AD, Moran B, Wilson NJ, Smith FJ, Goh CS, Sandilands A, Cole C, Barton GJ, Evans AT, Shimizu H, Akiyama M, Suehiro M, Konohana I, Shboul M, Teissier S, Boussofara L, Denguezli M, Saad A, Gribaa M, Dopping-Hepenstal PJ, McGrath JA, Brown SJ, Goudie DR, Reversade B, Munro CS, McLean WH. Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma Nat Genet. 2012 Nov;44(11):1272-6._x000D_ 7: Gómez-García AC, Salas-Alanís JC, Bar-Fernandez N, Mendoza-Meza R, Díaz-Montes SM, Fajardo-Ramírez OR. A novel AAGAB mutation in a Peruvian family with punctate palmoplantar keratoderma Acta Dermatovenerol Alp Pannonica Adriat. 2021 Mar;30(1):47-48._x000D_ 8: Harjama L, Karvonen V, Kettunen K, Elomaa O, Einarsdottir E, Heikkilä H, Kivirikko S, Ellonen P, Saarela J, Ranki A, Kere J, Hannula-Jouppi K. Hereditary palmoplantar keratoderma - phenotypes and mutations in 64 patients J Eur Acad Dermatol Venereol. 2021 Sep;35(9):1874-1880._x000D_ 9: Elhaji Y, Hedlin C, Nath A, Price EL, Gallant C, Northgrave S, Hull PR. AAGAB Mutations in 18 Canadian Families With Punctate Palmoplantar Keratoderma and a Possible Link to Cancer J Cutan Med Surg. 2020 Jan/Feb;24(1):28-32._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31200764">10: Bownes RJ, Turnbull AK, Martinez-Perez C, Cameron DA, Sims AH, Oikonomidou O. On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer Breast Cancer Res. 2019 Jun 14;21(1):73. </a>_x000D_ _x000D_ <strong>Products Related to Human AAGAB Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>