BAY-27-9955
BAY-27-9955 is an orally active non-peptide glucagon receptor antagonist. Bay 27-9955 competitively blocks the interaction of glucagon with the human glucagonreceptor at an IC50 value of 110 nM. BAY-27-9955 can be used for the study of type 2 diabetes[1].
Product Specifications
CAS Number
[202855-56-9]
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bay-27-9955.html
Smiles
OC(C)C1=C(C(C)C)C=C(C(C)C)C(CCC)=C1C2=CC=C(F)C=C2
Molecular Formula
C23H31FO
Molecular Weight
342.49
References & Citations
[1]K F Petersen, et al. Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans. Diabetologia. 2001 Nov;44 (11) :2018-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15212353 1 Vial
Lentiviral mouse Cd55 shRNA (UAS) - Lentiviral mouse Cd55 shRNA (UAS, RFP) plasmid
Ask
View Details 
126417 100 µg
ERAP1 (Endoplasmic Reticulum Aminopeptidase 1, ARTS-1, Adipocyte-derived Leucine Aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive Leucyl-specific Aminopeptidase, PILS-AP, Type 1 Tumor Necrosis Factor Receptor Shedding Aminopeptidase Regulator, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154)
Ask
View Details 218431 50 µg
PCMTD1, Recombinant, Human, aa1-220, His-Tag (Protein-L-Isoaspartate O-Methyltransferase Domain-Containing Protein 1)
Ask
View Details