A-61603
A-61603 is a selective α1A-adrenergic receptor agonist[1]. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro[2].
Product Specifications
CAS Number
[107756-30-9]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/a-61603.html
Purity
99.16
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
CS(=O)(NC1=C2CCCC(C3=NCCN3)C2=CC=C1O)=O.Br
Molecular Formula
C14H20BrN3O3S
Molecular Weight
390.30
References & Citations
[1]Meyer MD, et al. Synthesis and in vitro characterization of N-[5- (4,5-dihydro-1H-imidazol-2-yl) -2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: A novel selective α1A receptor agonist. J. Med. Chem. 39 (20), 4116-4119 (1996) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Available Sizes
Curated Selection
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