S-Nitroso-N-acetyl-DL-penicillamine
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation[1][2][3][4].
Product Specifications
CAS Number
67776-06-1
Product Name Alternative
SNAP
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/s-nitroso-n-acetyl-dl-penicillamine.html
Purity
98.84
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 11.11 mg/mL (ultrasonic)
Smiles
O=NSC(C)(C(C(O)=O)NC(C)=O)C
Molecular Formula
C7H12N2O4S
Molecular Weight
220.25
Precautions
H315, H319, H335
References & Citations
[1]E. Salas, et al. Comparative pharmacology of analogues of S-nitroso-N-acetyl-DL-penicillamine on human platelets. Br J Pharmacol. 1994 Aug;112 (4) :1071-6.|[2]Ioannidis I, et al. Enhanced release of nitric oxide causes increased cytotoxicity of S-nitroso-N-acetyl-DL-penicillamine and sodium nitroprusside under hypoxic conditions. Biochem J. 1996 Sep 15;318 (Pt 3) :789-95.|[3]Pravdic D, et al. Effect of nitric oxide donors S-nitroso-N-acetyl-DL-penicillamine, spermine NONOate and propylamine propylamine NONOate on intracellular pH in cardiomyocytes. Clin Exp Pharmacol Physiol. 2012 Sep;39 (9) :772-8.|[4]Mang CF, et al. Modulation of acetylcholine release in the guinea-pig trachea by the nitric oxide donor, S-nitroso-N-acetyl-DL-penicillamine (SNAP) . Br J Pharmacol. 2000 Sep;131 (1) :94-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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