Phospho-Shp1 (Tyr536) Rabbit FITC Conjugate

<strong>Phospho-Shp1 (Tyr536) Rabbit FITC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018701_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1, PTPN6, HCP, PTP1C_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rosenthal KM, Edwards LJ, Sabatino JJ Jr, Hood JD, Wasserman HA, Zhu C, Evavold BD. Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics PLoS One. 2012;7(3):e32562._x000D_ 2: Chen KF, Tai WT, Liu TH, Huang HP, Lin YC, Shiau CW, Li PK, Chen PJ, Cheng AL. Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3 Clin Cancer Res. 2010 Nov 1;16(21):5189-99._x000D_ 3: Liu SH, Sheu WH, Lee MR, Lee WJ, Yi YC, Yang TJ, Jen JF, Pan HC, Shen CC, Chen WB, Tien HR, Sheu ML. Advanced glycation end product Nε-carboxymethyllysine induces endothelial cell injury: the involvement of SHP-1-regulated VEGFR-2 dephosphorylation J Pathol. 2013 Jun;230(2):215-27._x000D_ 4: Su TH, Shiau CW, Jao P, Liu CH, Liu CJ, Tai WT, Jeng YM, Yang HC, Tseng TC, Huang HP, Cheng HR, Chen PJ, Chen KF, Kao JH, Chen DS. Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7243-8._x000D_ 5: Sayós J, Martínez-Barriocanal A, Kitzig F, Bellón T, López-Botet M. Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j Biochem Biophys Res Commun. 2004 Nov 12;324(2):640-7._x000D_ 6: Kundu S, Fan K, Cao M, Lindner DJ, Zhao ZJ, Borden E, Yi T. Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents J Immunol. 2010 Jun 1;184(11):6529-36._x000D_ 7: Wang CT, Lin CS, Shiau CW, Chu PY, Hsiao CC, Chiang YL, Tai WT, Chen KF. SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells J Orthop Res. 2013 Feb;31(2):335-42._x000D_ 8: Tai WT, Shiau CW, Chen HL, Liu CY, Lin CS, Cheng AL, Chen PJ, Chen KF. Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells Cell Death Dis. 2013 Feb 7;4(2):e485._x000D_ 9: Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3 Biochem Pharmacol. 2012 Mar 15;83(6):769-77._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9485206">10: Le Dréan E, Vély F, Olcese L, Cambiaggi A, Guia S, Krystal G, Gervois N, Moretta A, Jotereau F, Vivier E. Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases Eur J Immunol. 1998 Jan;28(1):264-76. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Shp1 (Tyr536) Rabbit FITC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>