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LpxC-IN-14

Product Specifications

UNSPSC Description

LpxC-IN-14 (compound 6i) is a potent LpxC inhibitor. LpxC-IN-14 shows antibacterial activity. LpxC-IN-14 shows low cytotoxicity. LpxC-IN-14 shows acceptable plasma protein binding[1].

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lpxc-in-14.html

Smiles

O=C(N[C@@H]([C@H](O)C)C(NO)=O)C1=CC=C(C#CC2=CC=C(/C=N/N3CCCC3)C=C2)C=C1

Molecular Weight

434.49

References & Citations

[1]Chen F, et al. Design, synthesis and evaluation of novel LpxC inhibitors containing a hydrazone moiety as Gram-negative antibacterial agents. Eur J Med Chem. 2024 Sep 21;279:116892.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-168100/LpxC-IN-14-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-168100/

Clinical Information

No Development Reported

Curated Selection

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