Phosphomannose isomerase

Phosphomannose isomerase is the first enzyme involved in the biosynthesis pathway of GDP-Man. Phosphomannose isomerase catalyzes the conversion between fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P) . Phosphomannose isomerase is important for cell wall synthesis and protein glycosylation. Phosphomannose isomerase is a potent antifungal target to curb the threats posed by A. flavus[1].

Product Specifications

CAS Number

[9023-88-5]

UNSPSC

12352204

Target

Fungal

Type

Enzyme

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/phosphomannose-isomerase.html

Solubility

10 mM in DMSO

Smiles

[Phosphomannoseisomerase]

References & Citations

[1]Usman S, et al. Phosphomannose Isomerase Is Involved in Development, Stress Responses, and Pathogenicity of Aspergillus flavus. Microbiol Spectr. 2022 Oct 26;10 (5) :e0202722.