TDI-011536
TDI-011536 is a potent Lats kinase inhibitor, interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration[1].
Product Specifications
CAS Number
2687970-96-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/tdi-011536.html
Purity
99.91
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CNC2=NC=CC=C12)/N=C(SC=C3CO)/N3CC4=CC=CC=C4
Molecular Formula
C19H16N4O2S
Molecular Weight
364.42
Precautions
H302, H315, H319
References & Citations
[1]Kastan NR, et al. Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs. Proc Natl Acad Sci U S A. 2022 Jul 12;119 (28) :e2206113119.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC403538 20 µg
GM CSF Receptor alpha (CSF2RA) (NM_172247) Human Over-expression Lysate
Sign In for Pricing
View Details 