Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

POT-4 (TFA)

POT-4 TFA (AL-78898A TFA), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 TFA can be used for age-related macular degeneration research[1][2].

Product Specifications

Product Name Alternative

AL-78898A (TFA)

UNSPSC

12352209

Target

Complement System

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pot-4-tfa.html

Solubility

10 mM in DMSO

Smiles

CN1C2=CC=CC=C2C(C[C@H]3C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N3)=O)C(C)C)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)C(N[C@H](C(N)=O)[C@H](O)C)=O)=O)CCCNC(N)=N)=O)CC4=CN=CN4)=O)C)=O)=O)CC5=CNC6=CC=CC=C56)=O)CC(O)=O)=O)CCC(N)=O)=O)=C1.O=C(O)C(F)(F)F

Molecular Formula

C74H103F3N22O20S2

Molecular Weight

1741.87

References & Citations

[1]S. Kaushal, et al. Complement C3 inhibitor POT-4: Clinical Safety of Intravitreal Administration. ARVO Annual Meeting Abstract, 2009 Apr.|[2]Robyn Troutbeck, et al. Therapeutic targeting of the complement system in age-related macular degeneration: a review. Clin Exp Ophthalmol. Jan-Feb 2012;40 (1) :18-26.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3204A/POT-4-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3204A/

Scientific Category

Peptides

Clinical Information

Phase 2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

UltraCruz® Syringe Filter, PVDF, 0.10 μm, 13 mm, 75/pack
sc-358809 75/Case

UltraCruz® Syringe Filter, PVDF, 0.10 μm, 13 mm, 75/pack

Ask
View Details
Atf6b Mouse shRNA Plasmid (Locus ID 12915)
TR509938 1 Kit

Atf6b Mouse shRNA Plasmid (Locus ID 12915)

Ask
View Details
CHRNB3 Protein, Human, Recombinant (ECD, hFc Tag)
PH52091M4 100 µg

CHRNB3 Protein, Human, Recombinant (ECD, hFc Tag)

Ask
View Details
Human TRANCE/RANK L/TNFSF11 Alexa Fluor 647 MAb (685857)
FAB6264R-100UG 100 µg

Human TRANCE/RANK L/TNFSF11 Alexa Fluor 647 MAb (685857)

Ask
View Details
3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde
OR1032329-01 100 mg

3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde

Ask
View Details
3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde
OR1032329-02 250 mg

3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde

Ask
View Details