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Bucladesine (GMP)

Product Specifications

UNSPSC Description

Bucladesine (Dibutyryl cAMP) (GMP) is a Bucladesine (HY-B0764B) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Bucladesine is a membrane permeable selective activator that activates cyclic adenosine phosphate dependent protein kinase A (PKA)[1].

Target Antigen

Phosphodiesterase (PDE); PKA

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease;Stem Cell/Wnt;TGF-beta/Smad

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bucladesine-gmp.html

Smiles

O=C(CCC)O[C@H]1[C@H](N2C(N=CN=C3NC(CCC)=O)=C3N=C2)O[C@@](CO4)([H])[C@@]1([H])OP4(O)=O

Molecular Weight

469.39

References & Citations

[1]Sharifzadeh M, et al. Post-training intrahippocampal infusion of nicotine–bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats[J]. European journal of pharmacology, 2007, 562(3): 212-220.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B0764G/Bucladesine-GMP-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B0764G/

Clinical Information

No Development Reported

CAS Number

362-74-3

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