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Aculene D

Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations[1].

Product Specifications

CAS Number

2043948-38-3

UNSPSC

12352211

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aculene-d.html

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@@](CC=C(C[C@@H]2O)C)([H])C(CC)=CC1=O

Molecular Formula

C14H20O2

Molecular Weight

220.31

References & Citations

[1]Kong FD, et al. Metabolites with Gram-negative bacteria quorum sensing inhibitory activity from the marine animal endogenic fungus Penicillium sp. SCS-KFD08. Arch Pharm Res. 2017;40 (1) :25-31.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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