DFF45 (Cleaved-Thr225) rabbit pAb
Function: Inhibitor of the caspase-activated DNase (DFF40). PTM: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 CIDE-N domain. subunit: Heterodimer of DFFA and DFFB.
Product Specifications
Background
Function:Inhibitor of the caspase-activated DNase (DFF40) ., PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 CIDE-N domain., subunit:Heterodimer of DFFA and DFFB.
UniProt
O00273
Swiss Prot
O00273
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human DFF45 (Cleaved-Thr225)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Molecular Weight
12 36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
12 36kD
Fragment
IgG
Subcellular Location
Cytoplasm.
Other Product Names
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD)
Gene ID (Human)
1676
Available Sizes
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