DFF45 (Cleaved-Thr225) rabbit pAb
Function: Inhibitor of the caspase-activated DNase (DFF40). PTM: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 CIDE-N domain. subunit: Heterodimer of DFFA and DFFB.
Product Specifications
Background
Synonyms
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)
Gene ID
1676
UniProt
O00273
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human DFF45 (Cleaved-Thr225)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Molecular Weight
12 36kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES19986-1.pdf
Observed Molecular Weight
12 - 36 kD
Subcellular Location
Cytoplasm.
Other Product Names
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD)
Gene ID (Human)
1676
SwissProt (Human)
O00273
Available Sizes
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