Aspartylglutamate
Aspartylglutamate (Asp-Glu) is a dipeptide that exhibits excitatory activity, as it has been shown to depolarize CA1 pyramidal neurons and increase conductance in response to stimulation. Aspartylglutamate selectively binds to certain glutamate receptors and demonstrates potent effects in specific regions of the hippocampus, particularly in the stratum radiatum where it enhances excitatory neurotransmission.
Product Specifications
CAS Number
6157-06-8
Product Name Alternative
Asp-Glu
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aspartylglutamate.html
Purity
99.79
Solubility
DMSO : 12 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C[C@H](N)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O
Molecular Formula
C9H14N2O7
Molecular Weight
262.22
References & Citations
[1]Dipeptides of glutamate and aspartate may be endogenous neuroexcitants in the rat hippocampal slice
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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