Dentonin (TFA)
Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism[1].
Product Specifications
Product Name Alternative
AC-100 (TFA)
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dentonin-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)[C@@H](C)O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CCCCN)=O)CC3=CC=CC=C3)=O)CCC2)=O)CCC(N)=O)=O)=O)CC(O)=O)=O)=O)CO)=O)CC4=CC=CC=C4)=O)CCC1)=O)CO)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(O)=O.OC(C(F)(F)F)=O
Molecular Formula
C109H161F3N30O44
Molecular Weight
2652.61
References & Citations
[1]Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26 (9) :1256-62.|[2]N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86 (8) :780-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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