1-Aminohydantoin (hydrochloride)

1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2].

Product Specifications

CAS Number

[2827-56-7]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-aminohydantoin-hydrochloride.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1NC(CN1N)=O.[H]Cl

Molecular Formula

C3H6ClN3O2

Molecular Weight

151.55

Precautions

H315, H319

References & Citations

[1]Tao Le, et al. A fluorescent immunochromatographic strip test using a quantum dot-antibody probe for rapid and quantitative detection of 1-aminohydantoin in edible animal tissues. Anal Bioanal Chem. 2018 Jan;410 (2) :565-572.|[2]Yong Tang, et al. Development of a lateral flow immunoassay (LFA) strip for the rapid detection of 1-aminohydantoin in meat samples. J Food Sci. 2011 Aug;76 (6) :T138-43.