GSK-4716
GSK-4716 is a selective ERRβ/γ agonist.
Product Specifications
CAS Number
101574-65-6
UNSPSC
12352005
Hazard Statement
H317, H400, H410
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/GSK-4716.html
Purity
99.63
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N/N=C/C1=CC=C(C(C)C)C=C1)C2=CC=C(O)C=C2
Molecular Formula
C17H18N2O2
Molecular Weight
282.34
Precautions
H317, H400, H410
References & Citations
[1]Wang SC, et al. An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells. Mol Cell Endocrinol. 2010 Feb 5;315 (1-2) :146-52.|[2]Rangwala SM, et al. Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity. J Biol Chem. 2010 Jul 16;285 (29) :22619-29.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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